Prof. Bruce Westley
(University of Newcastle)
Scientists have known for a long time that the female hormone oestrogen can increase the growth of breast tumours.
Drugs such as tamoxifen inhibit the effects of oestrogens and stop breast cancers growing. Other drugs called aromatase inhibitors prevent the synthesis of oestrogens. Unfortunately not everyone responds to treatment with these drugs. Patients who do respond frequently develop resistance. This project will examine other ways of preventing the progression of breast tumours.
Professor Westley will test the idea that drugs could be used to treat women who do not respond to hormone therapy or who have developed resistance to these drugs during their treatment.
